Nature

Conditional gene expression and RNAi using MEC-8–dependent splicing in C. elegans

Conditional expression of gene activity provides a means to examine gene function that is restricted in time or cell type and is particularly useful when complete elimination of gene activity leads to ...
Nature

SV40-derived vectors provide effective transgene expression and inhibition of HIV-1 using constitutive, conditional,and pol III promoters

Sequestering Tat by delivering TAR decoys is specifically advantageous for dealing with the high mutability of HIV-1, which is a major problem in HIV-1-infected patients. Escape from TAR decoy ...