Very few of the existing state-specific firearm laws are associated with reduced firearm mortality, and this evidence underscores the importance of focusing on relevant and effective firearms ...

This 3-paper Series reviews the evidence about the increase in ultra-processed foods in diets globally and highlights the association with many non-communicable diseases. This rise in ultra-processed ...

The initial successes of anti-amyloid β monoclonal antibodies offer new perspectives for improving the clinical trajectory of Alzheimer’s disease for the first time since its identification in 1906.

bDivision of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, USA cDivision of Infectious Diseases, Department of Medicine, McGill ...

An estimated 1.35 million people die every year from road traffic injuries (RTIs) and more than 50 million are injured or disabled despite a first decade of action and high-level global attention.

The global burden of disease amenable to surgical intervention, such as trauma, cancer, and complications from childbirth, is substantial and growing. Despite this, there are currently gross ...

Few topics are more emotive than child maltreatment. "Children, the most precious and vulnerable members of our societies, deserve closer attention to their care and education and better protection ...

In late 2022, the SARS-CoV-2 omicron BQ.1 and XBB lineages, characterised by amino acid substitutions in the spike (S) protein that increase viral fitness, had become predominant in the western (BQ.1) ...

"Despite the great attention western countries pay to the mind and human consciousness in philosophy and the arts, disturbances of mental health remain not only neglected but also deeply stigmatised ...

Widespread failures during the COVID-19 pandemic at multiple levels worldwide have led to millions of preventable deaths and a reversal in progress towards sustainable development for many countries.

aDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON L8N 3Z5, Canada bDepartment of Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada ...

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