AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.
A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.
CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.
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140,000 DNA loops mapped with AI to predict genome folding
A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...
Software version: R version 4.5.1 (2025-06-13) -- "Great Square Root" The out-of-sample forecast exercise and in-sample results were obtained on a high-performance cluster which allows for parallel ...
A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...
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